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Market participants will also look forward to re-examination of laws dealing with withholding tax on dividends.
Shares of RBL Bank shed 18.5%, after falling as much as 25% earlier in the session.
The NSE Nifty 50 index fell 1.4% to 16,745 by 0347 GMT and the benchmark S&P BSE Sensex was down 1.4% at 56,235.04.
The potentially more contagious Omicron was first reported to the WHO from South Africa on November 24.
The company's market valuation went past Rs 1 lakh crore mark and closed at Rs 1,04,438.88 crore on the BSE.
The 30-share BSE index ended 555.15 points or 0.93 per cent lower at 59,189.73. Similarly, the broader NSE Nifty tumbled 176.30 points or 0.99 per cent to 17,646.
Over the years, the frontline index has climbed several record levels. The index had reached the 10,000-mark for the first time on February 6, 2006.
Vodafone Idea soared over 9%, while larger peer Bharti Airtel was up 0.4%.
After touching a lifetime high of 57,625.26 during the session, the 30-share BSE Sensex ended 662.63 points or 1.16 per cent higher at its record close of 57,552.39.
Paytm's IPO plan comes at a time when several first-generation homegrown startups in India prepare to go public on domestic bourses.