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The win was Vettel's fourth of the season, 51st of his career, and once-dominant champions Mercedes' first defeat at Silverstone since 2012.
Hamilton is only a point behind Vettel after nine of 21 races and had hoped to retake the lead in front of his home crowd.
An emotional Lewis Hamilton put Mercedes on pole position for his home British Grand Prix after giving his all to stay ahead of Ferrari's Formula One championship leader Sebastian Vettel.
Ferrari's Kimi Raikkonen finished a close second, with team mate Vettel third against expectations after a grid penalty had demoted him to sixth on the grid.