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Badosa posted on social media that the injury has forced her to shut down her season.
This lawsuit stems from a heated confrontation that occurred earlier this year.
Ekaterina Alexandrova advanced to the last eight.
Fellow lefthander Draper played superb tennis to level the match at a set all but the 21-year-old soon developed leg troubles and was left groaning in pain as Nadal closed out the match on a warm and sunny afternoon at Rod Laver Arena.
It was Pegula's 41st match victory in WTA main draws this year, with only world No. 1 Iga Swiatek (62) and the second-ranked Ons Jabeur (46) winning more.
Greek fourth seed Sakkari kept alive her hopes of making the Finals by surviving an early scare and fighting back from a set down to beat American Danielle Collins 5-7, 6-3, 6-3.
No. 12 Coco Gauff and 20th-seeded Madison Keys set up a third-round match-up.
The former champion's choice of wardrobe for Monday's first-round match landed her in a spot of bother amid windy conditions
The 15-year-old from Manipur triumphed in the World Cadet Judo Championship in Sarajevo.
Vinesh Phogat made it three consecutive wins in Commonwealth Games.