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Variants crop up randomly, and new ones have the potential to be more dangerous than previous ones.
The second anniversary came at a time when we were reeling under the spell of an unexpected Omicron attack.
A study by Chinese researchers had concluded that a type of coronavirus, NeoCov, that spreads among bats in South Africa may pose a threat to humans in future if it mutates further.
Omicron is a "deviant" from the COVID-19 pandemic progression script and so it must be postulated that two pandemics are going on side by side, one by the Delta and close relatives and the other by the latest variant of concern, said noted virologist Dr T Jacob John.
The US pharmaceutical company made its comments as European countries geared up for further travel and social restrictions and a study warned that the rapidly spreading Omicron coronavirus variant was five times more likely to reinfect people than its predecessor, Delta.
Over 100 cases have been detected in South Africa, where the new strain is slowly becoming the dominant one.
Wuhan city is where the coronavirus first emerged in 2019 and spiralled into a pandemic.
In the study, researchers from China, the US, Belgium and Australia claimed to have unearthed game animals that are commonly hunted or consumed as exotic food in China.
A joint WHO-China inquiry had dismissed the possibility that the virus had emerged accidentally from a laboratory as 'extremely unlikely'.
Ex-Chinese Communist Party insider Wei Jingsheng said that the World Military Games in October 2019 may have acted as the virus' first superspreader event.