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Liverpool won 3-1 while Manchester City beat Everton 2-0 in an earlier match.
Liverpool moved five points clear atop the Premier League to set up a potential thriller on Sunday against third-placed Arsenal.
Uruguayan Nunez put the seal on a dominant Liverpool display with his second goal in stoppage time.
The 31-year-old Salah, who has 151 Premier League goals for Liverpool, changed his boots at halftime and the switch paid off handsomely.
Manchester City slipped out of the top four as Tottenham Hotspur made up ground with a third consecutive victory, beating Everton 2-1 at home.
Royals bought him only towards the fag end of the auction after his impactful spell in the second ODI against India.
Diogo Dalot was sent off in stoppage time for two yellow cards -- both for dissent.
Ten-man Chelsea beat Brighton & Hove Albion 3-2 at Stamford Bridge while fourth-placed Aston Villa needed a late Ollie Watkins goal to scrape a 2-2 draw at Bournemouth.
Mumbai Indians have traded their all-rounder Cameron Green to RCB in an all cash deal.
Trent Alexander-Arnold drilled in an 80th-minute equaliser with his right foot to deny City a 24th successive home win in all competitions.