Opener Shubman Gill and pacer Mohammed Siraj will make their debut in the second Test against Australia at the Melbourne Cricket Ground (MCG) here on Saturday.
Gill replaces an out-of-form Prithvi Shaw, while Siraj has come in for the injured Mohammed Shami.
India have also included a fit-again all-rounder Ravindra Jadeja and wicketkeeper Rishabh Pant in place of regular skipper Virat Kohli and Wriddhiman Saha in the playing eleven.
India have gone in with just five specialist batsmen – Mayank Agarwal, Gill, Cheteshwar Pujara, Ajinkya Rahane and Hanuma Vihari. K L Rahul has been overlooked yet again.
Rahane will leading India since Kohli has taken paternity leave.
India trail the four-match series 0-1 after losing the opening pink-ball Test in Adelaide by eight wickets inside three days.
Indian XI: Mayank Agarwal, Shubman Gill, Cheteshwar Pujara, Ajinkya Rahane (capt), Hanuma Vihari, Ravindra Jadeja, Rishabh Pant (wk), R Ashwin, Jasprit Bumrah, Umesh Yadav and Mohammed Siraj.