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Tuesday, Jun 10, 2025
Djokovic will end the year without a major for the first time since 2017.
The former champion was stunned by Dutchman Botic van de Zandschulp in straight sets.
Osaka lost to Karolina Muchova in the second round, unable to get to grips with the Czech's superb serve-and-volley tennis.
The Italian defeated American Alex Michelsen 6-4 6-0 6-2.
Romanian qualifier Elena-Gabriela Ruse won 6-4, 7-5 to reach the third round.
The green-and-white outfit drew inspiration from Japan's colourful, playful and self-expressive Harajuku style.
The 184th-ranked Evans, once the British number one, beat world number 22 Khachanov in five hours and 35 minutes.
Shelton showed he could be a threat over the next two weeks as he broke Thiem again to close out the second set.
The last time Djokovic played all four majors in a season without winning one was 14 years ago.
Djokovic, who has not competed since winning the gold medal at the Paris Olympics, will begin against a qualifier and is expected to meet Andrey Rublev in the quarterfinals and fourth seed Alexander Zverev in the semis.
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