London-born Carlo Acutis, the 15-year-old boy who is often referred to as 'God's influencer,' was canonised today by Pope Leo XIV. Acutis, who ran a website called miracolieucaristici.org to document catholic teachings, miracles and the like, died at the age of 15 (1991 - 2006). As per reports, he was diagnosed with Acute Promyelocytic Leukaemia aka APL, a type of rare, life-threatening blood cancer. He died within a week at the St Gerald Hospital, Italy. It is triggered by a genetic mutation, which results in uncontrollable multiplication of the white blood cells in the bone marrow, according to the Cleveland Clinic. In many patients, it comes on suddenly and gets worse in no time. As for what causes the genetic mutation, experts are not sure yet on what triggers it. 

Why APL has high mortality rate
Health experts say that the disease results in cancer-specific protein granules, called Cancer Procoagulant,  getting released into a person's bloodstream. This destroys the various agents in the blood that help it clot. APL quickly progresses and immunocompromises patients. Even in those who are cured, relapse is extremely common. Carlo died on October 11, 2006. His remains are at the St Mary Major Parish aka the Shrine of the Renunciation, in Assisi.

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