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It was Srikanth’s first semifinal on the BWF Tour since the Hylo Open in 2022.
The 24-year-old from Guwahati suffered a 13-21, 12-21 loss to world No. 17 Supanida in a 35-minute clash.
An inspired Tai Tzu Ying secured her first women's singles India Open title with a dominating straight-game win over Chen Yu Fei.
Sathish, who won men's singles title at India International and had a runner-up finish at Maldives International this season, prevailed over Ayush in an exciting final.
The world No.1 pair of Liang Wei Keng and Wang dashed the Indian duo's hopes of claiming a second BWF Super 750 title.
The top seeds will face another Chinese pair in the summit clash.
Young Indian Priyanshu Rajawat also exited the season's last BWF Super 750 event.
The Asian Games bronze medallist Indian, who returned to action after recovering from a back injury, squandered an opening game advantage to lose narrowly to world No. 12 Chen.
Last week, the 28-year-old was forced to concede her second round match against Thailand's Supanida Katethong at the French Open.
It was Kiran's second BWF World Tour Super 100 title.