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Prannoy lost 21-18, 15-21, 8-21 to sixth seed Chou Tien Chen of Chinese Taipei.
Sindhu defeated Japan’s sixth seed Tomoka Miyazaki, 21-15, 8-21, 21-17.
No shuttler from the country could advance to the second round of the tournament.
The women's doubles pair of Treesa Jolly and Gayatri Gopichand lost to top seeds Chen Qing Chen and Jia Yi Fan of China.
Saina lost to world No. 8 South Korea's Sung Ji-hyun 22-10, 8-21, 14-21 in the opening round.
PV Sindhu rallied to down Busanan Ongbamrungphan of Thailand 21-23, 21-13, 21-18.
India's top shuttler Sindhu beat Xuerui 21-18, 21-12 in just 34 minutes to seal a place in the pre-quarterfinals.
World No. 26 Satwik and Ashwini showed their grit as they recovered from a mid-game slump to outwit sixth seeds Praveen Jordan and Melati Daeva Oktavianti 22-20, 17-21, 21-17.
Almost a month after dispatching Ginting en route to his World Championships bronze at Basel, world No. 15 Praneeth went down to the 21-16, 6-21, 16-21 in 55 minutes to end his campaign.
Doubles specialist Satwiksairaj Rankireddy also had a dismal day as he suffered twin defeats, losing both the men's doubles and mixed doubles pre-quarterfinals.
Results 1-10 of 16