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Fritz, assured of breaking into the top 10 after beating Canada's Denis Shapovalov in the semifinals, also won titles in Eastbourne and Indian this year.
The 30-year-old played out of his skin and saved three match points, only to endure the agony of losing it in the end, as Chou emerged victorious in a pulsating contest.
Prannoy saw off eighth-seeded Loh 22-20, 21-19 in a 44-minute clash.
It was Srikanth's first win over his Malaysian opponent Lee Zii Jia in four meetings.
Djokovic started the Japan Open by taking part in a doubles game and switched to higher gears as the week progressed, never allowing his opponents, including world number 15 David Goffin, to pose a serious threat.
Djokovic posted some pics of his experience with the wrestlers on his Instagram handle with a caption in which he expressed his admiration for the sport and revealed that he used to follow it a lot in his childhood.
Sindhu suffered her second straight defeat at the hands of Japanese Akane Yamaguchi as she went down 18-21, 15-21 in the women's singles quarterfinals.
H S Prannoy, who had knocked out Kidambi Srikanth in the opening round, lost to Rasmus Gemke of Denmark 9-21, 15-21.
HS Prannoy defeated compatriot Kidambi Srikanth, while Sameer Verma went down to Anders Antonsen.
The unseeded Praneeth recorded a comfortable 21-17, 21-13 win over the Japanese shuttler Kento Nishimoto in just 42 minutes.