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Man City harvested a near-record amount of goals in destroying Watford to the tune of an 8-0 win at the Etihad Stadium.
Bournemouth profited from first-half goals by Nathan Ake and Harry Wilson, but had to fight off a home resurgence after the break before wrapping up the points with a Callum Wilson goal to end a run of 15 previous games without a win at Saints.
The Video Assistant Referee was heavily involved early on after Wilfred Ndidi had bundled the ball into the net, only for the effort to be ruled out for offside.
Prince Abdullah, a grandson of the founder of Saudi Arabia, took full control of the Yorkshire club on Monday when co-owner Kevin McCabe was ordered by a high court to sell a 50 per cent share to him after a legal battle lasting over 20 months.
With four wins out of four to start the season, Juergen Klopp's side head into the international break in buoyant mood after another convincing display from the European champions.
Arsenal have seven points while Spurs are on five from four games.
United, who were without injured French internationals Paul Pogba and Anthony Martial, were far from convincing but manager Ole Gunnar Solkskjaer was delighted they secured their second win of the campaign to reach eight points from five games.
Liverpool came from behind to earn a 3-1 home win over Newcastle United thanks to Sadio Mane's first-half double and a late goal from Mo Salah on Saturday.
In echoes of last season's epic Premier League title race, Liverpool and Manchester City matched each other stride for stride to eke out 2-1 victories on Saturday when both had looked set for shock defeats.
Tottenham are still without an away league win since January and are in 11th spot, 10 points behind fourth-placed Chelsea.
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