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The Oscar triumph followed a Screen Actors Guild Award for her performance and capped the third Academy Award nomination of her career.
He won the Best Supporting Actor for his role as a fisherman and father in family drama "CODA."
Directed by Ryusuke Hamaguchi, "Drive My Car" was adapted from a short story by Haruki Murakami.
Rather than turn the Oscars ceremony into a megaphone for messages about Ukraine, the show's directors opted for a silent message that did not mention Russia.
Catch live updates of the winners list here.
31-year-old DeBose earned mainstream acclaim for her lively portrayal of Anita, an outspoken Puerto Rican woman who showcases her singing and dancing talents in the song "America."
The Oscars have returned to their traditional venue, the Dolby Theatre in LA, which will be filled to about three-quarters capacity with 2,500 guests.
The event takes place at the Dolby Theatre in Hollywood, Los Angeles, California. Actors Tracee Ellis Ross and Leslie Jordan announced the nominations on February 8, 2022.
The ten movies competing at the 94th Academy Awards cover a wide range of genres from sci-fi, road movie, sports drama to political satire.
The scheme will allow members of the public, charities, businesses and community groups to offer accommodation to refugees to come to Britain even if they do not have family ties.
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