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Victims of fighting over the past 48 hours remain lying on roads where fighting continues or trapped under rubble, the authorities said.
Three senior Iranian officials have said that only a ceasefire deal in Gaza would hold Iran back from direct retaliation against Israel for the assassination of Hamas leader Ismail Haniyeh on its soil last month.
The CPI leader was part of a small group that led a protest march to the Israel embassy demanding ceasefire in Gaza.
Sinwar, who spent half his adult life in Israeli prisons, was the most powerful Hamas leader left alive following the assassination of Haniyeh
The Islamist faction mourned the death of Haniyeh, who it said was killed in “a treacherous Zionist raid on his residence in Tehran.”
The media office and the Gaza health ministry said more than 100 people were wounded.
Displaced people sheltering in the area said their tents were torn down by the force of the strike.
Israeli army fought Hamas and Islamic Jihad militants in the heaviest combat.
Palestinians have reacted cautiously ahead of Israel's response saying they're exhausted and can't stand more setbacks and disappointments.
The latest casualties bring the total Palestinian death toll to 37,834, with 86,858 injuries reported since the outbreak of the Palestinian-Israeli conflict.