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Harris also called for the establishment of a Palestinian state
He mentioned the conflicts in Ukraine, Gaza, Myanmar and other countries, saying 'let us not forget war is a defeat'.
The latest escalation comes a day after it hit Houthi targets Hodeidah port.
Displaced people sheltering in the area said their tents were torn down by the force of the strike.
While tanks withdrew from some areas, Israeli snipers and tanks continued to control some high ground.
Israeli army fought Hamas and Islamic Jihad militants in the heaviest combat.
About 120 hostages remain captive after more than 100 hostages were released as part of a November cease-fire deal.
Palestinians have reacted cautiously ahead of Israel's response saying they're exhausted and can't stand more setbacks and disappointments.
The latest casualties bring the total Palestinian death toll to 37,834, with 86,858 injuries reported since the outbreak of the Palestinian-Israeli conflict.
Israel's air and ground offensive has killed more than 37,400 people in the Hamas-ruled Palestinian territory, according to health authorities there.