Those seeking treatment will be specifically asked whether they have come in contact with anyone returning from China, officials said.
The BSL-3 modular facility has been set up at its new campus located in Aakkulam.
The death toll has increased to 5,31,564 with 17 deaths, which includes seven reconciled by Kerala.
India recorded 10,262 cases in the week ending April 20 and marked rise in positivity rate.
The state recorded 2,484 cases on Wednesday
The active cases to 60,313 and the death toll increased to 5,31,141 with 27 deaths.
India had reported 7,830 coronavirus infections on Wednesday.
The death toll due to the disease has increased to 5,31,016.
The death toll has increased to 5,30,929 with 13 deaths -- two each reported from Karnataka and Maharashtra, one each from Kerala and Punjab, and seven reconciled by Kerala, the data updated at 8 am stated.
The active cases now comprise 0.05 per cent of the total infections and the national COVID-19 recovery rate was recorded at 98.76 per cent, the ministry said.