Opting to bowl, Eagles bowled out Tigers for 106 in 20 overs. Player-of-the-match Fanoos was the wrecker-in-chief with figures of 3/22.
Tigers amassed 211/4 in 20 overs after opting to bat. Nikhil smashed 57 off 35 balls, while Basith remained unbeaten on 54 off 26 balls. Krishnan came up with a 35-ball 54.
Kerala pacer Basil Thampi bagged two wickets for the South Zone while Het Patel remains unbeaten on 96.
The two Kerala players are part of the 15-member squad that will be led by Hanuma Vihari.
Kerala wicketkeeper-batters Vishnu Vinod and Mohammed Azharuddeen went unsold on the opening day of the auction.
Sijomon Joseph and Basil Thampi had claimed five wickets between them as Kerala had restricted Chandigarh to 184/8 earlier.
After restricting Assam to 121/8, Kerala chased down the target in 18 overs with opener Rohan Kunnummal making an unbeaten 56.
Earlier, pacer Basil Thampi's triple strikes helped Kerala restrict Bihar to 131/5 .
Pacer Basil Thampi has opted out citing personal emergency.
The home side made 255 in reply to Kerala's first innings total of 162. Unlike Kerala, Andhra adopted a disciplined batting approach and their innings lasted 111.1 overs.