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Spaniard Sainz was handed a 10-place grid penalty through no fault of his own after a metal drain cover came loose and wrecked his speeding car when it drove over it, forcing the cancellation of opening practice.
The pole-to-flag victory, for the fourth year in a row under the Yas Marina floodlights, left the 26-year-old alone in third place in Formula One's all-time list of winners.
Charles Leclerc finished second after starting on pole position, losing and regaining the lead and then losing it again before passing Sergio Perez on the final lap to deny Red Bull a seventh one-two of the season.
On a nightmare afternoon for Mexican teammate Sergio Perez, who retired after colliding at the first corner with Ferrari's Charles Leclerc, the Dutch 26-year-old also equalled French great Alain Prost's haul of 51 career wins.
Williams rookie Logan Sargeant celebrated a surprise first point in Formula One on Sunday.
Formula One leader Max Verstappen ran away with the Japanese Grand Prix from pole position on Sunday as his dominant Red Bull team secured the constructors' title for the second year in a row. The victory at Suzuka was the Dutch driver's 13th in 16 races this season and left him on the verge of a
McLaren's Lando Norris and Mercedes' Lewis Hamilton completed the top three.
Bernardo Viana also told Reuters the lawyers had agreed to give Formula One and the sport's governing body, the FIA, until mid-October to respond to a Letter Before Claim sent to them on August 15. The legal team had initially set a Friday deadline.
The Red Bull driver won on his home soil to equal Sebastian Vettel's record from 2013.
London-based Enyo Law said Brazilian Massa, now 42, had been 'the victim of a conspiracy committed by individuals at the highest level of F1 together with the FIA and Formula One Management'.