Mbappe, who turned down Real and signed a new three-year deal at PSG last month, topped the list with an estimated transfer value of 205.6 million euros ($219.5 million), beating Vinicius (185.3 million euros) and Haaland (152.6 million euros).
Mbappe was widely tipped for a move to the Spanish capital but signed a contract extension until 2025 at PSG last week in a dramatic U-turn, a decision that irked many Real players and fans.
Mbappe had been widely tipped to join Real Madrid this summer but stunned the Spanish champions by signing a contract extension until 2025 with PSG last week.
Fan tokens are a type of cryptocurrency that allow holders to vote on mostly minor decisions related to their clubs.
The Argentine talisman scored a goal in their 3-0 win over Venezuela in the World Cup qualifier.
PSG missed several chances and were thwarted by Real keeper Thibaut Courtois, who denied Mbappe on several occasions before superbly pushing away Messi's spot kick in the second half.
Defender Juan Bernat, back-up goalkeeper Sergio Rico and midfielder Nathan Bitumazala were the other players who returned positive tests.
Holders Chelsea will face French champions Lille, just as they were drawn in the original draw, while six-times champions Bayern Munich will now face RB Salzburg.
PSG also advanced to the last 16 thanks to Leipzig's win over Club Brugge but the loss highlighted their continued problems in finding an effective way to harness their star-studded attack.
The Dutchman, who had struggled this season after joining from Liverpool, struck in the 21st minute and headed in another goal six minutes before halftime.