Thiruvananthapuram will host Elite Group B matches, with Greenfield Stadium and St Xavier's KCA Cricket Ground being the venues.
The current COVID-19 situation in the country has forced the BCCI to cut down the number of venues from six to two.
It will be the third T20I to be played at the Greenfield International Stadium.
The KCA backed out of the series after the state government decided to conduct an army recruitment rally at the Greeenfield International Stadium, Karyavattom, during the same period.
West Indies' dominance was evident by the half-dozen sixes that they hit apart from 11 boundaries compared to five maximums by the hosts.
India pulled off their highest successful run chase in a T20I on Friday night as they chased down a challenging 207/5, posted by the Windies, in 18.4 overs.
Three cities that are in the fray to be new IPL venues are Lucknow, Guwahati and Thiruvananthapuram.
Sanju decided to contribute two-game match fee to the groundsmen of Greenfield International Stadium in Thiruvananthapuram.
This will be second T20I to be staged at the Greenfield International Stadium.