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The double Olympic medallist has found the going tough ever since returning from a five-month long lay-off following an ankle injury.
It was Kiran's second BWF World Tour Super 100 title.
No shuttler from the country could advance to the second round of the tournament.
The women's doubles pair of Treesa Jolly and Gayatri Gopichand lost to top seeds Chen Qing Chen and Jia Yi Fan of China.
South Korea clinched its first singles gold at the BWF world championships through An Se-young.
At 31, the Thiruvananthapuram native is now India's biggest medal hope at next year's Paris Olympics.
The Indian ace lost the semifinal 21-18, 13-21, 14-21 to the World No. 3.
The India pair lost to Denmark's Kim Astrup and Anders Skaarup Rasmussen in straight games.
World No. 11 Lakshya Sen, a winner of bronze medal at the 2021 edition, however, couldn't get past Thailand's Kunlavut Vitidsarn.
The most successful Indian at World Championships with five medals, Sindhu lacked any sting in her attack and went down tamely 14-21 14-21 to old nemesis Nozomi Okuhara of Japan, a 2017 gold medallist and silver winner in 2019.