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Forlan will team up with current world No. 101 Federico Coria of Argentina in the main draw at the clay court Challenger Tour event in Montevideo after being given a wild card.
Diaz scored more Premier League goals against United than any other opponent.
Huerzeler, 31, has overseen two victories to keep Brighton provisionally top of the standings after two games
Man United supporters are expecting better than their eighth-placed finish last term.
Erik ten Hag's team looked on course to repeat their shock victory over City in the FA Cup final when Alejandro Garnacho put United ahead after 82 minutes, but City midfielder Bernardo Silva netted a minute from time to send the match to penalties.
Mainoo and Garnacho scored in the 2-1 win for United at Wembley
Manchester City, who are aiming for an unprecedented fourth consecutive English top-flight title, can retake the lead when they play at Arsenal's London rivals Tottenham Hotspur on Tuesday.
Casemiro missed a spot kick for United in the shootout but they hit back and Rasmus Hojlund's penalty sent them into the final against Manchester City.
Silva sidefooted the ball home in the 84th minute after Chelsea goalkeeper Djordje Petrovic parried a shot from former Blues midfielder Kevin De Bruyne.
With seven games remaining in the neck-and-neck title race, Liverpool and Arsenal have 71 points with the Gunners leading on goal difference. Holders Manchester City are third on 70 points, while United are sixth.